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Completed Research Programs National Tissue Engineering Center

It was said...

"The data says it all. If it weren't for the seed funding provided by PTEI I might not have received subsequent related NIH funding for this work. I have also branched into urethral tissue engineering in large part because of the success of the blood vessel tissue engineering work. Both of these areas focus on engineering a muscular tube."

David A. Vorp, PhD
Associate Professor, Surgery and Bioengineering and Director, Vascular Bioengineering Laboratory, University of Pittsburgh

The U.S. Congress, in 2002, established the National Tissue Engineering Center (NTEC) to develop and deliver regenerative therapies treatment of military personnel — in combat situations and also following injury.

PTEI administers NTEC funding, identifying and recruiting teams of scientists to advance therapies so that our best and bravest receive the most modern trauma care when they are wounded in action, and the most advanced in-hospital and restorative care upon their return home.

NTEC research seeks to restore the function of damaged tissues and organs and replace tissue lost from severe trauma. Key research is focused on:


  • Designing surgical adhesives, sealants and hemostatus that will revolutionize wound closure
  • Understanding the molecular determinants of scarless wound healing
  • Developing bone regenerative therapies for craniofacial wounds
  • Verifying that a bioresorable scaffold bulk-seeded with stem cells and cultured in-vitro will yield a vascular graft suitable for implantation.
  • Evaluating the use of amnion-derived pluripotential cells for early, rapid wound closure of partial-thickness and full-thickness burns 


The NTEC consortium includes scientists and clinicians from the following: